Advancements In 3D Printing For Pharmaceutical Applications: A Systematic Review
Keywords:
Three-Dimensional Printing (3DP), Personalized Medicine,Drug Delievery, Innovation,Drug-Release ProfilesAbstract
The advent of three-dimensional (3D) printing
technology in medicine allows the pharmaceutical
sector to participate in the fourth industrial
revolution. 3D printing technology is a
groundbreaking and essential method for
fabricating solid objects through the layer-bylayer
deposition process under computer
supervision. Three-dimensional (3D) printed
medicines may serve as an essential instrument
for comprehending individualized treatments
tailored to the distinct needs of each patient,
encompassing factors such as age, weight, comorbidities,
and pharmacogenetic and
pharmacokinetic attributes. 3D printing
technology provides a distinct advantage over
traditional methods in the domain of new drug
delivery systems (NDDS). Many 3D printing
techniques utilized encompass inkjet printers,
thermal inkjet printers, fused deposition modeling,
and hot melt extrusion, among others. The uses of
3D printing in the pharmaceutical sector are
many, including lab-grown organs, drug delivery
systems, anatomical models, and customized
medications, among others.3D printing is
considered a valuable, efficient, and economical
instrument with the capacity to transform the
future of general pharmacy practice, particularly
in pharmacological therapy.
Downloads
References
1. Preethy Ani Jose. 3D Printing of
Pharmaceuticals- A Potential Technology in
Developing Personalized Medicine. Asian
Journal of Pharmaceutical Research and
Development. 2018; 6(3): 46-54. DOI:
http://dx.doi.org/10.22270/ajprd.v6.i3.375
2. Mathew E, Pitzanti G, Larraneta E, et
al. 3D Printing of Pharmaceuticals and Drug
Delivery Devices. Pharmaceutics. 2020; 12: 266.
3. Ubaid T, Mohammed M. Three
Dimensional Dug Printing: A Revolution in
Pharmaceutical Science. PharmaTutor. 2019; 7
(3): 19-25. http://dx.doi.org/10.29161/
PT.v7.i3.2019.19
4. Gujrati A, Sharma A, Mahajan SC. Review
on Applications of 3D Printing in
Pharmaceuticals. Int. J. Sci. Rev. Res. 2019; 25:
148 -154.
5. Asad Ali, Usama Ahmad and Juber Akhtar.
3D Printing in Pharmaceutical Sector: An
Overview, Pharmaceutical Formulation Design -
Recent Practices, Usama Ahmad and Juber Akhtar,
IntechOpen, DOI: 10.5772/intechopen.90738.
Available from: https://
www.intechopen.com/books/pharmaceuticalformulation-
design-recent-practices/3d- printing-inpharmaceutical-
sector-an-overview
6. Ghadge S, Nagesh A, Suresh S. A Decisive
Overview on Three Dimensional Printing in
Pharmaceuticals. Journal of Drug Delivery and
Therapeutics. 2019; 9(3): 591-598.
7. L. Srinivas et al. 3D Printing in
Pharmaceutical Technology: A Review. Int. Res. J.
Pharm. 2019; 10(2): 8-17
http://dx.doi.org/10.7897/2230-8407.100234
8. Meléndez PA, Kane KM, Ashvar CS, et al.
Thermal Inkjet Application in the Preparation of
Oral Dosage Forms, Dispensing of Prednisolone
Solutions and Polymorphic Characterization by
Solid State Spectroscopic Techniques; Journal of
Pharmaceutical Sciences. 2008; 97(7): 2619-2636.
9. M. Singh, et al. Inkjet Printing—Process and
its Applications; Advanced Materials. 2010: 673-
685
10. Fina F, Madla CM, Goyanes A, et al.
Fabricating 3D Printed Orally Disintegrating
Printlets Using Selective Laser Sintering.
International Journal of Pharmaceutics. 2018;
541(1–2): 101–107.
11. Hoy MB. 3D Printing, Making Things at the
Library; Med Ref Serv Q. 2013; 32(1):94-99.
12. Gokhare Vinod G, Dr. Raut D.N, Dr. Shinde
D.K. A Review paper on 3D-Printing Aspects and
Various Processes Used in the 3D-Printing.
International Journal of Engineering Research &
Technology. 2017; 6(6): 953-958.
13. Klein GT, Lu Y, Wang MY. 3D Printing and
Neurosurgery-Ready for Prime Time? Word
Neurosurg. 2013; 80(3-4): 233-235.
14. Schubert C, Van Langeveld MC, Donodo LA.
Innovations in 3D Printing: A 3D Overview from
Optics to Organs. The British Journal of
Ophthalmology. 2014; 98(2): 159-161.
15. Ozbolat IT, Yu Y. Bioprinting towards Organ
Fabrication: Challenges and Future Trends. IEEE
Transactions on Biomedical Engineering. 2012; 60(3): 691-699.
16. Mertz L. Dream It, Design It, Print It In 3-D,
What Can 3D Printing Do For You? IEEE Pulse.
2013; 4(6): 15-21.
17. Bartlett S. Printing Organs on Demand.
Lancet Respiratory Medicine. 2013; 1(9): 684.
18. Ursan I, Chiu L, Pierce A. Three Dimensional
Drug Printing, a Structured Review. J. Am Pharma
Assoc. 2013; 53(2): 136-144.
19. Lipson H. New World of 3D Bioprinting
Offers Completely New Ways of Thinking: Q &
A with Author, Engineer, and 3 -D Printing Expert
Hod Lipson. IEEE Pulse. 2013; 4(6): 12-14.
20. Gu Y, Chen X, Lee JH et al. Inkjet Printed
Antibiotic- and Calcium-Eluting Bioresorbable
Nanocomposite Micropatterns for Orthopedic
Implants. Acta Biomaterialia. 2018; 8(1): 424-431.
21. Agrawal A, Gupta AK. 3D Printing
Technology in Pharmaceuticals and Biomedical: A
Review. Journal of Drug Delivery and
Therapeutics. 2019; 9(2-A): 1-4.
22. Maulvi FA, Shah MJ, Solanki BS, et al.
Application of 3D Printing Technology in the
Development of Novel Drug Delivery Systems. Int
J Drug Dev & Res. 2017; 9: 44-49.
23. Wu BM, Cima MJ. Effects of Solvent-
Particle Interaction Kinetics on Microstructure
Formation during Three-Dimensional Printing,
Polymer Engineering & Science. 1999; 39: 249-
260.
24. Kulkarni P, Marsan A, Dutta D. A Review of
Process Planning Techniques in Layered
Manufacturing, Rapid Prototyping Journal. 2000;
6: 18-35.